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Co enzyme Q 10

 Stroke patient (69 year old) with low energy levels and tardive dyskinesia




What is Co-Q 10?

Ubiquinone or Co Q10 is a vitamin like substance and is a cofactor of an enzyme. It is present in the mitocondrial membranes where it is involved in the energy production. 

The most common Coenzyme Q in human mitochondria is Co Q10. 'Q'  represents quinone head and 10 refers to the number of isoprene repeats in the tail. 

Dietary CoQ10-supplementation was associated with demonstrable benefits in CPZ-induced Parkinsonism-like changes in mice. Clinical effects have not been well studied in humans.

Meat (10-120 mg/kg) and oils (10-280 mg/kg) are the richest sources of dietary Co Q10


References:

1. Onaolapo OJ, Odeniyi AO, Jonathan SO, Samuel MO, Amadiegwu D, Olawale A, Tiamiyu AO, Ojo FO, Yahaya HA, Ayeni OJ, Onaolapo AY. An Investigation of the Anti-Parkinsonism Potential of Co-enzyme Q10 and Co-enzyme Q10 /Levodopa-carbidopa Combination in Mice. Curr Aging Sci. 2021;14(1):62-75. doi: 10.2174/1874609812666191023153724. PMID: 31702498.

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