Skip to main content

Co enzyme Q 10

 Stroke patient (69 year old) with low energy levels and tardive dyskinesia




What is Co-Q 10?

Ubiquinone or Co Q10 is a vitamin like substance and is a cofactor of an enzyme. It is present in the mitocondrial membranes where it is involved in the energy production. 

The most common Coenzyme Q in human mitochondria is Co Q10. 'Q'  represents quinone head and 10 refers to the number of isoprene repeats in the tail. 

Dietary CoQ10-supplementation was associated with demonstrable benefits in CPZ-induced Parkinsonism-like changes in mice. Clinical effects have not been well studied in humans.

Meat (10-120 mg/kg) and oils (10-280 mg/kg) are the richest sources of dietary Co Q10


References:

1. Onaolapo OJ, Odeniyi AO, Jonathan SO, Samuel MO, Amadiegwu D, Olawale A, Tiamiyu AO, Ojo FO, Yahaya HA, Ayeni OJ, Onaolapo AY. An Investigation of the Anti-Parkinsonism Potential of Co-enzyme Q10 and Co-enzyme Q10 /Levodopa-carbidopa Combination in Mice. Curr Aging Sci. 2021;14(1):62-75. doi: 10.2174/1874609812666191023153724. PMID: 31702498.

Comments

Post a Comment

Popular posts from this blog

Mounjaro, Is it a game changer for weight loss and diabetes?

  MOUNJARO™ ( Tirzepatide) was approved for medical use in the United States in May 2022 WEIGHT LOSS: (Not approved by FDA for weight loss) Eli Lilly and Company is  finalizing an application to the U.S. Food and Drug Administration for fast-track approval to sell tirzepatide for chronic weight management. MOUNJARO™ is a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist indicated in adults for type 2 diabetes mellitus management. CONTRAINDICATIONS Personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2  Known serious all to tirzepatide or any of the excipients in MOUNJARO                                                                    ...
Post a Comment
Read more

Respiratory syncytial virus (RSV) ---cough

Respiratory syncytial virus (RSV) is a leading cause of severe lower respiratory tract disease in young children. Recent RSV strain in Utah is  causing moderate to severe cough (especially during night), weakness and cold-like symptoms .  RSV infection is sometimes severe and is associated with hospitalization, mechanical ventilation, long-term complications, decreased quality of life, loss of work productivity and patient/caregiver stress.  RSV may cause inflammation and infection of small airways and lungs.  Recovery time usually ranges from 7 to 14 days, but RSV can cause serious disease. RSV combined with increasing flu circulation are keeping some hospitals and pharmacies occupied.  Seventeen states are reporting that more than 80% of beds are full, according to the data. Children’s hospitals in Utah, Arizona, the District of Columbia, Maine, Minnesota, Rhode Island, and Kentucky are almost completely at capacity. RSV can spread when viral droplets from a ...
Post a Comment
Read more

Sodium chloride Tablets USP

A 91- year old patient. Admitted to the hospital from the ED. Patient was seen for altered mental status. Labs, CT of brain head, CXR XR of left Tib/Fib were performed. Presumed meningioma in the left middle cranial fossa was noted. Sodium was critically low at 114. Nephrologist was consulted and hyponatremia is of unknown etiology. Patient also has uncontroled hypertension. Comorbidities: Coronary artery disease, Diabetes, Dementia, hypothyroidism, hyperlipedemia, neuropathy. Patient will need physicain oversight for hyponatremia, normal saline routinely, and medication management for hypertension. Rx: Sodium Chloride USP 1.0 gram Use  1. Hyponatremia 2. Preparation of normal isotonic solution of sodium chloride 3. As an electrolyte replenisher for the prevention of heat cramps, due to excessive  perspiration 4. any alternate use as directed by a physician Each tablet contains: sodium 394mg Hyponatremia  is a common electrolyte disorder encountered i...
7 comments
Read more