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Dronabinol 2.5 mg capsules (Nausea, vomiting and loss of appetite in AIDS and Cancer patients)

Dronabinol 2.5 mg capsules



Contraindicated: with Metronidazole and Disulfiram

Drug Classes: Antiemitic, Appetite enhancer, Cannabinoid   

FDA approved uses:

Chemotherapy-induced nausea and vomiting

HIV/AIDS - Loss of appetite

AIDS - Loss of appetite

(Capsule) Initial, 2.5 mg orally twice daily, before lunch and dinner; titration, adjust based on optimal clinical response and tolerance; may increase dosage gradually to 2.5 mg before lunch and 5 mg before dinner, and then to 5 mg twice daily as tolerated; MAX, 20 mg/day in divided doses  

Chemotherapy-induced vomiting, In patients with inadequate response to commonly used antiemetic treatments
  • (Capsule) Initial, 5 mg/m(2) orally 1 to 3 hours prior to chemotherapy, then 5 mg/m(2) every 2 to 4 hours after chemotherapy for a total of 4 to 6 doses/day; titration, adjust dosage based on response and tolerance; may increase dose in increments of 2.5 mg/m(2); MAX, 15 mg/m(2)/dose
Side effects:

Serious
  • Immunological hypersensitivity
  • Cardiovascular: Hypotension (1% or less ), Tachycardia (Greater than 1% )
  • Psychiatric: Depression (1% or less ), Mania, Schizophrenia
Non -serious

Gastrointestinal, pain, palpitations, vomiting, anxiety, euphoria and hallucinations

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